Article
Measurements of Hydrogen Peroxide and Oxidative DNA Damage in a Cell Model of Premature Aging.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2020
Iglesias-Pedraz Juan Manuel, Comai Lucio
Abstract excerpt
Reactive oxygen species (ROS) represent a number of highly reactive oxygen-derived by-products generated by the normal mitochondrial respiration and other cellular metabolic reactions. ROS can oxidize macromolecules including lipids, proteins, and nucleic acids. Under physiological condition, the cellular levels of ROS are controlled by several antioxidant enzymes. However, an imbalance between ROS production and...
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