Article
Comparison of gyrA and parC mutations and resistance levels among fluoroquinolone-resistant isolates and laboratory-derived mutants of oral streptococci.
The Journal of antimicrobial chemotherapy - 1 Jun 2000
Kaneko A, Sasaki J, Shimadzu M, Kanayama A, Saika T, Kobayashi I
Abstract excerpt
Laboratory-derived fluoroquinolone-resistant mutants were obtained by serial passage of Streptococcus sanguis and Streptococcus anginosus isolates on agar containing increasing concentrations of old and new fluoroquinolones, ofloxacin and DU-6859a, respectively. Sequencing of an S. sanguis isolat...
Topics
- Anti-Infective Agents
- DNA Gyrase
- DNA Topoisomerase IV
- DNA Topoisomerases, Type II
- Drug Resistance, Microbial
- Fluoroquinolones
- Microbial Sensitivity Tests
- Mutation
- Streptococcus
- Streptococcus sanguis