Article
Fluoroquinolone resistance mutations in the parC, parE, and gyrA genes of clinical isolates of viridans group streptococci.
Antimicrobial agents and chemotherapy - 1 Nov 1998
González I, Georgiou M, Alcaide F, Balas D, Liñares J, de la Campa A G
Abstract excerpt
The nucleotide sequences of the quinolone resistance-determining regions (QRDRs) of the parC and gyrA genes from seven ciprofloxacin-resistant (Cpr) isolates of viridans group streptococci (two high-level Cpr Streptococcus oralis and five low-level Cpr Streptococcus mitis isolates) were determine...
Topics
- Amino Acid Sequence
- Anti-Infective Agents
- Base Sequence
- Ciprofloxacin
- DNA Gyrase
- DNA Topoisomerase IV
- DNA Topoisomerases, Type II
- Drug Resistance, Microbial
- Genes, Bacterial
- Humans
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Streptococcus
- Transformation, Genetic