Article
Natural resistance-associated macrophage protein 1 polymorphisms are associated with microscopy-positive tuberculosis.
The Journal of infectious diseases - 15 Aug 2002
Søborg Christian, Andersen Aase B, Madsen Hans O, Kok-Jensen Axel, Skinhøj Peter, Garred Peter
Abstract excerpt
The natural resistance-associated macrophage protein 1 (NRAMP1) is implicated in the pathophysiology of mycobacterial infections. We investigated by polymerase chain reaction previously published Nramp1 genotypes at 4 loci-INT4, N543D, 3'UTR, and 5'(CA)(n) microsatellite markers-in 104 human immunodeficiency virus-negative patients with tuberculosis and 176 healthy control subjects living in Denmark. No...
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