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Article

Apolipoprotein E epsilon4 allele is associated with the volume of white matter changes in patients with lacunar infarcts.

European journal of neurology - 1 Nov 2006

Wen H M, Baum L, Cheung W S, Mok V, Lam W W M, Tomlinson B, Wong K S, Ng H K

Abstract excerpt

The relationship between the apolipoprotein E (APOE) exon 4 polymorphism and white matter changes (WMC) in elderly subjects or patients with Alzheimer's disease is controversial. To investigate this polymorphism in relation to WMC in patients with lacunar infarcts, we prospectively observed 67 patients with acute lacunar infarct and 134 age- and sex-matched controls. Genotypes were determined using a nested...

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Source

Identifiers

PMID: 17038035
DOI: 10.1111/j.1468-1331.2006.01436.x

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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