Article
A gain-of-function screen for genes that affect the development of the Drosophila adult external sensory organ.
Genetics - 1 Jun 2000
Abdelilah-Seyfried S, Chan Y M, Zeng C, Justice N J, Younger-Shepherd S, Sharp L E, Barbel S, Meadows S A, Jan L Y, Jan Y N
Abstract excerpt
The Drosophila adult external sensory organ, comprising a neuron and its support cells, is derived from a single precursor cell via several asymmetric cell divisions. To identify molecules involved in sensory organ development, we conducted a tissue-specific gain-of-function screen. We screened 2293 independent P-element lines established by P. Rorth and identified 105 lines, carrying insertions at 78 distinct...
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