Partial suppression of the fission yeast rqh1(-) phenotype by expression of a bacterial Holliday junction resolvase.

doi:10.1093/emboj/19.11.2751

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Article

Partial suppression of the fission yeast rqh1(-) phenotype by expression of a bacterial Holliday junction resolvase.

The EMBO journal - 1 Jun 2000

Doe C L, Dixon J, Osman F, Whitby M C

Abstract excerpt

A key stage during homologous recombination is the processing of the Holliday junction, which determines the outcome of the recombination reaction. To dissect the pathways of Holliday junction processing in a eukaryote, we have targeted an Escherichia coli Holliday junction resolvase to the nuclei of fission yeast recombination-deficient mutants and analysed their phenotypes. The resolvase partially complements...

Topics

Cell Nucleus
DNA Helicases
DNA, Fungal
Endodeoxyribonucleases
Escherichia coli
Escherichia coli Proteins
Eukaryotic Cells
Fungal Proteins
Genes, Reporter
Genes, Synthetic
Genetic Complementation Test

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Green Fluorescent Proteins

Holliday Junction Resolvases

Luminescent Proteins

Models, Genetic

Nuclear Localization Signals

Nuclear Proteins

Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 10835372
DOI: 10.1093/emboj/19.11.2751
PMCID: PMC212752

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