Article
Cancer risk and low-penetrance susceptibility genes in gene-environment interactions.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Jun 2000
Shields P G, Harris C C
Abstract excerpt
PURPOSE: To provide a concise review for human cancer risk related to low-penetrance genes and their effects on environmental carcinogen exposure. METHODS: Citation of relevant and recent references for molecular epidemiology, focusing on lung cancer, ethical issues, and some clinical implications of recent molecular epidemiology studies. RESULTS: Low-penetrance genes contribute to cancer risk by augmenting the...
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