Article
The use of common genetic polymorphisms to enhance the epidemiologic study of environmental carcinogens.
Biochimica et biophysica acta - 1 Jan 2001
Rothman N, Wacholder S, Caporaso N E, Garcia-Closas M, Buetow K, Fraumeni J F
Abstract excerpt
Overwhelming evidence indicates that environmental exposures, broadly defined, are responsible for most cancer. There is reason to believe, however, that relatively common polymorphisms in a wide spectrum of genes may modify the effect of these exposures. We discuss the rationale for using common...
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