Article
Comparison of TP53 mutations identified by oligonucleotide microarray and conventional DNA sequence analysis.
Cancer research - 15 May 2000
Wen W H, Bernstein L, Lescallett J, Beazer-Barclay Y, Sullivan-Halley J, White M, Press M F
Abstract excerpt
As the rate of gene discovery accelerates, more efficient methods are needed to analyze genes in human tissues. To assess the efficiency, sensitivity, and specificity of different methods, alterations of TP53 were independently evaluated in 108 ovarian tumors by conventional DNA sequence analysis and oligonucleotide microarray (p53 GeneChip). All mutations identified by oligonucleotide microarray and all...
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