Article
Infection-susceptibility alleles of mannose-binding lectin are associated with increased carotid plaque area.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 May 2000
Hegele R A, Ban M R, Anderson C M, Spence J D
Abstract excerpt
The MBL gene, encoding mannose-binding lectin, determines interindividual variation in susceptibility to certain infectious agents, such as Chlamydia pneumoniae. We examined whether infection-susceptibility alleles of MBL, called "non-A alleles," would be associated with increased carotid plaque area (CPA), an intermediate phenotype of atherosclerosis. In 164 subjects, we measured CPA with 2-dimensional...
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