Article
Association of Chlamydia pneumoniae with coronary artery disease and its progression is dependent on the modifying effect of mannose-binding lectin.
Circulation - 27 Aug 2002
Rugonfalvi-Kiss Szabolcs, Endrész Valéria, Madsen Hans O, Burián Katalin, Duba Jenô, Prohászka Zoltán, Karádi István, Romics László, Gönczöl Eva, Füst George, Garred Peter
Abstract excerpt
BACKGROUND: The possible association between coronary artery disease (CAD) and Chlamydia pneumoniae (C pneumoniae) infection is controversial. On the basis of the recent suggestion that mannose-binding lectin (MBL) variant alleles are related to an increased risk of severe atherosclerosis, and on the in vitro interaction of MBL with C pneumoniae, we asked whether MBL might contribute to CAD in conjunction with C...
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