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Mannose-binding lectin genotype and invasive pneumococcal infection.

Human immunology - 1 Aug 2006

Moens Leen, Van Hoeyveld Erna, Peetermans Willy E, De Boeck Christiane, Verhaegen Jan, Bossuyt Xavier

Abstract excerpt

Invasive pneumococcal disease is a serious infection that primarily affects young children and elderly or immunocompromised persons, but it also can affect healthy persons. Mannose-binding lectin (MBL) is a mediator of innate host immunity that activates the complement pathway and directly opsonizes pathogens. Variant structural codon and promoter MBL alleles have been associated with susceptibility to...

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PMID: 16916656
DOI: 10.1016/j.humimm.2006.04.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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