Article
Individuals with schizophrenia have an increased incidence of the H2R649G allele for the histamine H2 receptor gene.
Molecular psychiatry - 1 Dec 1996
Orange P R, Heath P R, Wright S R, Ramchand C N, Kolkeiwicz L, Pearson R C
Abstract excerpt
We have previously described an allelic variant of the human H2R, nominated the H2R649G allele. This allele contains an adenine-->guanidine substitution at base 649, which introduces an additional TaqI restriction endonuclease site into the gene. With this in mind, we have investigated allelic polymorphism of this receptor and its association with schizophrenia. H2R DNA from 47 schizophrenic patients and 46...
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