Article
No association between schizophrenia and the serotonin receptor 5HTR2a in an Italian population.
American journal of medical genetics - 21 Feb 1997
Verga M, Macciardi F, Cohen S, Pedrini S, Smeraldi E
Abstract excerpt
A major role of the serotonergic system has been hypothesized in the pathogenesis of schizophrenia, mostly based on the evidence of action of new and atypical neuroleptics such as Risperidone or Clozapine. We evaluated the genotypes and alleles of the 5HT2a receptor gene in 67 nuclear families following the Haplotype Relative Risk (HRR) strategy and in a second sample of 100 schizophrenics and 103 controls. The...
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