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Article

The isolation and characterization of missense mutants in the general repressor protein Ssn6 of Saccharomyces cerevisiae.

Molecular & general genetics : MGG - 1 Apr 2000

Limbach M P, Zitomer R S

Abstract excerpt

Ssn6, a TPR repeat-containing protein, associates with the Tup1 protein to form a general transcriptional repression complex in Saccharomyces cerevisiae. As part of a genetic analysis of this complex, we targeted mutations to the TPR repeat-coding region of the SSN6 gene, and applied selection for constitutive expression of the hypoxic gene ANB1. All but one of the resulting mutants failed to express full-length...

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Source

Identifiers

PMID: 10821179
DOI: 10.1007/s004380051189

Genes

TPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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