Article
Synergistic release from glucose repression by mig1 and ssn mutations in Saccharomyces cerevisiae.
Genetics - 1 May 1994
Vallier L G, Carlson M
Abstract excerpt
In the yeast Saccharomyces cerevisiae, glucose repression of SUC2 transcription requires the SSN6-TUP1 repressor complex. It has been proposed that the DNA-binding protein MIG1 secures SSN6-TUP1 to the SUC2 promoter. Here we show that a mig1 deletion does not cause nearly as dramatic a loss of repression as ssn6: glucose-grown mig1 mutants display 20-fold lower SUC2 expression than ssn6 mutants. Thus, repression...
Topics
- DNA-Binding Proteins
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Glucose
- Mutation
- Nuclear Proteins
- Protein Serine-Threonine Kinases
- Repressor Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins