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Article

Osteoarthritis-susceptibility locus on chromosome 11q, detected by linkage.

American journal of human genetics - 1 Jul 1999

Chapman K, Mustafa Z, Irven C, Carr A J, Clipsham K, Smith A, Chitnavis J, Sinsheimer J S, Bloomfield V A, McCartney M, Cox O, Cardon L R, Sykes B, Loughlin J

Abstract excerpt

We present a two-stage genomewide scan for osteoarthritis-susceptibility loci, using 481 families that each contain at least one affected sibling pair. The first stage, with 272 microsatellite markers and 297 families, involved a sparse map covering 23 chromosomes at intervals of approximately 15 cM. Sixteen markers that showed evidence of linkage at nominal P</=.05 were then taken through to the second stage,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10364529
DOI: 10.1086/302465
PMCID: PMC1378087

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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