Article
Linkage analysis of a region on chromosome 2 with essential hypertension in Chinese families.
Chinese medical journal - 1 May 2002
Zhu Dingliang, Huang Wei, Wang Houyi, Xiong Momiao, Chu Shaoli, Jin Li, Wang Guliang, He Xin, Yuan Wentao, Qian Yuecheng, Zhao Guangsheng
Abstract excerpt
OBJECTIVE: To verify the linkage of the candidate regions identified in a previous study (markers D2S168, D2S151, D2S142 on chromosome 2) with hypertension in Chinese families. METHODS: A genetic linkage study focused on chromosome 2 was performed on 240 Chinese families containing 856 patients with essential hypertension. A total of 1080 individuals were genotyped using 9 highly polymorphic microsatellite...
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