Article
Control of bisecting GlcNAc addition to N-linked sugar chains.
The Journal of biological chemistry - 4 Aug 2000
Fukuta K, Abe R, Yokomatsu T, Omae F, Asanagi M, Makino T
Abstract excerpt
In the present study, experimental control of the formation of bisecting GlcNAc was investigated, and the competition between beta-1,4-GalT (UDP-galactose:N-acetylglucosamine beta-1, 4-galactosyltransferase) and GnT-III (UDP-N-acetylglucosamine:beta-d-mannoside beta-1, 4-N-acetylglucosaminyltransferase) was examined. We isolated a beta-1,4-GalT-I single knockout human B cell clone producing monoclonal IgM and...
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