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Article

Presence of a Gs alpha mutation in an adrenal tumor expressing LH/hCG receptors and clinically associated with Cushing's syndrome.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Feb 2000

Bugalho M J, Li X, Rao C V, Soares J, Sobrinho L G

Abstract excerpt

We describe the case of a patient with Cushing's syndrome due to a functioning adrenal adenoma. There was a pronounced increase in serum and urinary cortisol after administration of human chorionic gonadotropin. Immunocytochemistry revealed positive immunostaining for LH/hCG receptors. Molecular analysis documented the presence of a gsp mutation at codon 201 (CGT to TGT). The existence of this type of...

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Share to Adrenal Gland Neoplasms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Dehydroepiandrosterone Sulfate

Share to GTP-Binding Protein alpha Subunits, Gs

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Share to Receptors, LH

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Source

Identifiers

PMID: 10813107
DOI: 10.3109/09513590009167660

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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