Article
A polymorphism in the gene encoding CART is not associated with obesity in Pima Indians.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Apr 2000
Walder K, Morris C, Ravussin E
Abstract excerpt
Cocaine- and amphetamine-regulated transcript (CART) is a hypothalamic peptide that may be involved in the regulation of food intake. We screened the human CART gene and identified a novel C-->G substitution in the 3'-untranslated region of exon 3. This polymorphism was genotyped in a total of 68 Pima Indians with extremes of BMI. The frequencies for alleles C and G were 0.76 and 0.24, respectively. There was no...
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