Article
Analysis of sequence variability in the CART gene in relation to obesity in a Caucasian population.
BMC genetics - 11 Apr 2005
Guérardel Audrey, Barat-Houari Mouna, Vasseur Francis, Dina Christian, Vatin Vincent, Clément Karine, Eberlé Delphine, Vasseur-Delannoy Valérie, Bell Christopher G, Galan Pilar, Hercberg Serge, Helbecque Nicole, Potoczna Natascha, Horber Fritz F, Boutin Philippe, Froguel Philippe
Abstract excerpt
BACKGROUND: Cocaine and amphetamine regulated transcript (CART) is an anorectic neuropeptide located principally in hypothalamus. CART has been shown to be involved in control of feeding behavior, but a direct relationship with obesity has not been established. The aim of this study was to evaluate the effect of polymorphisms within the CART gene with regards to a possible association with obesity in a Caucasian...
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