Article
mdm2 mRNA level is a prognostic factor in soft tissue sarcoma.
Molecular medicine (Cambridge, Mass.) - 1 Jan 2000
Taubert H, Koehler T, Meye A, Bartel F, Lautenschläger C, Borchert S, Bache M, Schmidt H, Würl P
Abstract excerpt
BACKGROUND: The oncogenic properties of murine double minute-2 (mdm2) protein over-expression, which mostly results from the interaction with the tumor suppressor p53, are well described and their negative impacts on the prognosis of affected patients is well characterized. However, clinical relevance of mdm2 mRNA expression is poorly investigated. MATERIALS AND METHODS: In this study, 65 soft tissue sarcoma...
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