Article
The use of single-nucleotide polymorphism maps in pharmacogenomics.
Nature biotechnology - 1 May 2000
McCarthy J J, Hilfiker R
Abstract excerpt
Single-nucleotide polymorphisms (SNPs), common variations among the DNA of individuals, are being uncovered and assembled into large SNP databases that promise to enable the dissection of the genetic basis of disease and drug response (i.e., pharmacogenomics). Although great strides have been made in understanding the diversity of the human genome, such as the frequency, distribution, and type of genetic...
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