Article
Single nucleotide polymorphisms in clinics: Fantasy or reality for cancer?
Critical reviews in clinical laboratory sciences - 1 Jan 2016
Srinivasan Srilakshmi, Clements Judith A, Batra Jyotsna
Abstract excerpt
Single nucleotide polymorphisms (SNPs) have been classically used for dissecting various human complex disorders using candidate gene studies. During the last decade, large scale SNP analysis, i.e. genome-wide association studies (GWAS) have provided an agnostic approach to identify possible genetic loci associated with heterogeneous disease such as cancer susceptibility, prognosis of survival or drug response....
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