Article
beta1B integrin subunit contains a double lysine motif that can cause accumulation within the endoplasmic reticulum.
Journal of cellular biochemistry - 1 Apr 2000
Kee W J, Li E R, Watt F M
Abstract excerpt
Human epidermal keratinocytes are one of the few cell types that express the beta1B splice variant of the beta1 integrin subunit. Although in transfection experiments beta1B acts as a dominant negative inhibitor of cell adhesion, we found that beta1B was expressed at very low levels in keratinocytes, both in vivo and in culture, and had a predominantly cytoplasmic distribution, concentrated within the endoplasmic...
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