Article
p16(INK4a) gene alterations are frequent in lesions of mycosis fungoides.
The American journal of pathology - 1 May 2000
Navas I C, Ortiz-Romero P L, Villuendas R, Martínez P, García C, Gómez E, Rodriguez J L, García D, Vanaclocha F, Iglesias L, Piris M A, Algara P
Abstract excerpt
Mycosis fungoides is usually an indolent disease that, after a variable period of time in a stable phase, evolves into a tumoral form with aggressive behavior. The molecular events that mark this progression remain essentially unknown to date, and this prompted us to investigate the hypothetical role of p16(INK4a) silencing in mycosis fungoides progression. We analyzed the three most frequent mechanisms of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
