Effects of local transcription and H-NS on inversion of the fim switch of Escherichia coli.

doi:10.1046/j.1365-2958.2000.01864.x

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Article

Effects of local transcription and H-NS on inversion of the fim switch of Escherichia coli.

Molecular microbiology - 1 Apr 2000

O'Gara J P, Dorman C J

Abstract excerpt

The fim switch of Escherichia coli is responsible for phase-variable expression of type 1 fimbriae. Switching in the ON-to-OFF and OFF-to-ON directions is promoted by the FimB recombinase, while the FimE recombinase directs switching predominantly in the ON-to-OFF direction. The effects of local promoter activity and the H-NS nucleoid-associated protein on inversion of the switch were assessed. In contrast to...

Topics

Alleles
Bacterial Proteins
Base Sequence
DNA-Binding Proteins
Escherichia coli
Escherichia coli Proteins
Fimbriae, Bacterial
Gene Expression Regulation, Bacterial
Integrases
Molecular Sequence Data
Mutagenesis, Site-Directed
Promoter Regions, Genetic
Recombination, Genetic
Repressor Proteins
Sequence Analysis, DNA
Transcription, Genetic

Source

Open in PubMed

Identifiers

PMID: 10792731
DOI: 10.1046/j.1365-2958.2000.01864.x

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