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Article

Effects of local transcription and H-NS on inversion of the fim switch of Escherichia coli.

Molecular microbiology - 1 Apr 2000

O'Gara J P, Dorman C J

Abstract excerpt

The fim switch of Escherichia coli is responsible for phase-variable expression of type 1 fimbriae. Switching in the ON-to-OFF and OFF-to-ON directions is promoted by the FimB recombinase, while the FimE recombinase directs switching predominantly in the ON-to-OFF direction. The effects of local promoter activity and the H-NS nucleoid-associated protein on inversion of the switch were assessed. In contrast to...

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Share to Escherichia coli Proteins
Share to Fimbriae, Bacterial
Share to Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Mutagenesis, Site-Directed

Share to Recombination, Genetic

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Source

Identifiers

PMID: 10792731
DOI: 10.1046/j.1365-2958.2000.01864.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effects of local transcription and H-NS on inversion of the fim switch of Escherichia coli.PMID 10792731Read ↗

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Lrp stimulates phase variation of type 1 fimbriation in Escherichia coli K-12.Semantic proximity Read ↗

Promoter-specific repression of fimB expression by the Escherichia coli nucleoid-associated protein H-NS.Semantic proximity Read ↗

The site-specific recombination system regulating expression of the type 1 fimbrial subunit gene of Escherichia coli is sensitive to changes in DNA supercoiling.Semantic proximity Read ↗

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Thermal regulation of fimA, the Escherichia coli gene coding for the type 1 fimbrial subunit protein.Semantic proximity Read ↗

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Integration host factor stimulates both FimB- and FimE-mediated site-specific DNA inversion that controls phase variation of type 1 fimbriae expression in Escherichia coli.Semantic proximity Read ↗

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Rapid site-specific DNA inversion in Escherichia coli mutants lacking the histonelike protein H-NS.Semantic proximity Read ↗

Leucine-responsive regulatory protein plays dual roles as both an activator and a repressor of the Escherichia coli pap fimbrial operon.Semantic proximity Read ↗

Inversion-independent phase variation of type 1 fimbriae in Escherichia coli.Semantic proximity Read ↗

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