Article
The leucine-responsive regulatory protein binds to the fim switch to control phase variation of type 1 fimbrial expression in Escherichia coli K-12.
Journal of bacteriology - 1 Sept 1994
Gally D L, Rucker T J, Blomfield I C
Abstract excerpt
Phase variation of type 1 fimbriation in Escherichia coli is associated with the site-specific recombination of a 314-bp DNA invertible element. The fim switch directs transcription of fimA, the major fimbrial subunit gene, in one orientation (on) but not the other (off). Switching requires eithe...
Topics
- Bacterial Proteins
- Base Sequence
- Binding Sites
- DNA, Bacterial
- DNA-Binding Proteins
- Escherichia coli
- Escherichia coli Proteins
- Fimbriae Proteins
- Fimbriae, Bacterial
- Gene Expression Regulation, Bacterial
- Integrases
- Leucine-Responsive Regulatory Protein
- Molecular Sequence Data
- Mutation
- Recombination, Genetic
- Transcription Factors
- Transcription, Genetic