Article
Inversion-independent phase variation of type 1 fimbriae in Escherichia coli.
Journal of bacteriology - 1 Jul 1993
McClain M S, Blomfield I C, Eberhardt K J, Eisenstein B I
Abstract excerpt
The roles of fimB and fimE in the phase-variable expression of type 1 fimbriae in Escherichia coli were examined. A method was developed to study the effects of fimB and fimE on both recombination of the fim invertible element and fimbrial expression. The method used an allelic exchange procedure consisting of two steps. The first step, construction of intermediate strains, deleted fimB and fimE. This step locked...
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