Article
Tracking Alzheimerʼs disease in transgenic mice using fluorodeoxyglucose autoradiography
1 Apr 2000
Abstract excerpt
While transgenic mice have great promise in the study of Alzheimer's disease (AD), uncertainties remain about the extent to which they provide a model of the disorder or the best way to characterize disease progression. Using fluorodeoxyglucose (FDG) autoradiography, we found that transgenic mice over-expressing a mutant form of the human amyloid precursor protein have preferentially and progressively reduced...
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