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Article

Transgenic mice and modeling Alzheimer's disease.

Reviews in the neurosciences - 1 Jan 2000

Higgins L S, Cordell B

Abstract excerpt

The etiology of Alzheimer's disease (AD) is poorly understood, and no effective therapies are available. Although histopathology of the disease has been studied thoroughly, the relationship of various AD lesions to pathological processes and to dementia are debated. Progress would be greatly enhanced by existence of manipulable small animal models of the disease. Recently, transgenic strategies to developing such...

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PMID: 8564026
DOI: 10.1515/revneuro.1995.6.2.87

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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