Article
Absence of hSNF5/INI1 mutation in human lung cancer.
Cancer letters - 29 May 2000
Manda R, Kohno T, Hamada K, Takenoshita S, Kuwano H, Yokota J
Abstract excerpt
Frequent occurrence of chromosome 22q deletions in lung cancer indicates the presence of a tumor suppressor gene on this chromosome arm. The hSNF5/INI1 gene at chromosome 22q11.2 has recently been shown to act as a tumor suppressor in rhabdoid tumors. To investigate whether the hSNF5/INI1 gene located on chromosome 22q is involved in lung carcinogenesis, mutation analysis of the hSNF5/INI1 gene was performed...
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