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Article

IkappaB kinase alpha (IKKalpha) regulation of IKKbeta kinase activity.

Molecular and cellular biology - 1 May 2000

Yamamoto Y, Yin M J, Gaynor R B

Abstract excerpt

Two related kinases, IkappaB kinase alpha (IKKalpha) and IKKbeta, phosphorylate the IkappaB proteins, leading to their degradation and the subsequent activation of gene expression by NF-kappaB. IKKbeta has a much higher level of kinase activity for the IkappaB proteins than does IKKalpha and is m...

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Identifiers

PMID: 10779355
DOI: 10.1128/MCB.20.10.3655-3666.2000
PMCID: PMC85658

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10779355-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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