Article
A study of human growth hormone and insulin gene regions in relation to metabolic control of non-insulin-dependent diabetes mellitus.
Metabolism: clinical and experimental - 1 Apr 2000
Lucarelli P, Gloria-Bottini F, Antonacci E, Borgiani P, Palmarino R, Bottini E
Abstract excerpt
The possible association of human growth hormone (hGH) and insulin (INS) gene regions with metabolic control in diabetes was investigated in 98 subjects with non-insulin-dependent diabetes mellitus (NIDDM); 54 control subjects from the same population were also studied. Two polymorphic restriction sites in the region of the hGH cluster (BGLIIA and BGLIIB) show significant association with both glycemic and...
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