Article
DNA polymorphisms in the human tyrosine hydroxylase/insulin/insulin-like growth factor II chromosomal region in relation to glucose and insulin responses.
Diabetologia - 1 Jan 1993
Sten-Linder M, Wedell A, Iselius L, Efendic S, Luft R, Luthman H
Abstract excerpt
The feasibility of disease association studies using polymorphic DNA markers in the tyrosine hydroxylase/insulin/insulin-like growth factor II chromosomal region was indicated by a high degree of linkage disequilibrium found in haplotypes. Haplotypes were resolved in the parents from Scandinavian...
Topics
- Alleles
- Base Sequence
- Blood Glucose
- Chromosome Mapping
- Chromosomes, Human, Pair 11
- DNA Restriction Enzymes
- Deoxyribonucleases, Type II Site-Specific
- Diabetes Mellitus, Type 2
- Female
- Genotype
- Haplotypes
- Humans
- Insulin
- Insulin-Like Growth Factor II
- Male
- Middle Aged
- Molecular Sequence Data
- Oligodeoxyribonucleotides