Article
Genome scans provide evidence for low-HDL-C loci on chromosomes 8q23, 16q24.1-24.2, and 20q13.11 in Finnish families.
American journal of human genetics - 1 May 2002
Soro Aino, Pajukanta Päivi, Lilja Heidi E, Ylitalo Kati, Hiekkalinna Tero, Perola Markus, Cantor Rita M, Viikari Jorma S A, Taskinen Marja-Riitta, Peltonen Leena
Abstract excerpt
We performed a genomewide scan for genes that predispose to low serum HDL cholesterol (HDL-C) in 25 well-defined Finnish families that were ascertained for familial low HDL-C and premature coronary heart disease. The potential loci for low HDL-C that were identified initially were tested in an independent sample group of 29 Finnish families that were ascertained for familial combined hyperlipidemia (FCHL),...
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