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Article

Characterization of Bax-sigma, a cell death-inducing isoform of Bax.

Biochemical and biophysical research communications - 21 Apr 2000

Schmitt E, Paquet C, Beauchemin M, Dever-Bertrand J, Bertrand R

Abstract excerpt

The Ced-9/Bcl-like family of genes codes for proteins that have antiapoptotic and proapoptotic activity. Several Bax isoproteins have been detected by 2-D gel electrophoresis, and a novel human member, designated as Bax-sigma, has been identified and cloned from human cancer promyelocytic cells. Bax-sigma contains BH-3, BH-1, and BH-2 domains, putative alpha-5 and alpha-6 helices, and the carboxy-terminal...

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Identifiers

PMID: 10772918
DOI: 10.1006/bbrc.2000.2537

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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