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Article

BAX Redistribution Induces Apoptosis Resistance and Selective Stress Sensitivity in Human HCC

31 May 2020

Abstract excerpt

Cancer therapies induce differential cell responses, ranging from efficient cell death to complete stress resistance. The BCL-2 proteins BAX and BAK govern the cellular decision between survival and mitochondrial apoptosis. Therefore, the status of BAX/BAK regulation can predict the cellular apoptosis predisposition. Relative BAX/BAK localization was analyzed in tumor and corresponding non-tumor samples from 34...

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PMID: 32486514
DOI: 10.3390/cancers12061437

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