Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pro-apoptotic gene BAX is a pan-cancer predictive biomarker for prognosis and immunotherapy efficacy

5 Jul 2024

Abstract excerpt

BACKGROUND: Apoptosis Regulator BCL2 Associated X (BAX) is a pro-apoptotic gene. Apoptosis is one of the important components of immune response and immune regulation. However, there is no systematic pan-cancer analysis of BAX. METHODS: Original data of this study were downloaded from TCGA databases and GTEX databases. We conducted the gene expression analysis and survival analysis of BAX in 33 types of cancer...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell death mechanisms and regulation
Share to Ferroptosis and cancer prognosis
Share to Phagocytosis and Immune Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39074253
DOI: 10.18632/aging.206003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pro-apoptotic gene BAX is a pan-cancer predictive biomarker for prognosis and immunotherapy efficacyPMID 39074253Read ↗

Prognostic value and susceptibility of BAX rs4645878 polymorphism in cancer: A systematic review and meta-analysis.Semantic proximity Read ↗

BAX inhibitor‐1: between stress and survivalSemantic proximity Read ↗

Association of Bax Expression and Bcl2/Bax Ratio with Clinical and Molecular Prognostic Markers in Chronic Lymphocytic LeukemiaSemantic proximity Read ↗

Bax inhibitor-1: a highly conserved endoplasmic reticulum-resident cell death suppressorSemantic proximity Read ↗

An Apoptosis-Related Specific Risk Model for Breast Cancer: From Genomic Analysis to Precision MedicineSemantic proximity Read ↗

BAX Redistribution Induces Apoptosis Resistance and Selective Stress Sensitivity in Human HCCSemantic proximity Read ↗

A pan-cancer analysis of the oncogenic role of Bcl2-associated athanogene 2(BAG2) in human tumorsSemantic proximity Read ↗

Clinical significance of bax/bcl-2 ratio in chronic lymphocytic leukemiaSemantic proximity Read ↗

Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance.Semantic proximity Read ↗

Expression of pro‐apoptotic Bax and anti‐apoptotic Bcl‐2 proteins in human retinoblastomaSemantic proximity Read ↗

Hematopoietic malignancies demonstrate loss-of-function mutations of BAX.Semantic proximity Read ↗

The expression of a new variant of the pro-apoptotic molecule Bax, Baxpsi, is correlated with an increased survival of glioblastoma multiforme patientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.