Article
Chemokine receptor CCR2b 64I polymorphism and its relation to CD4 T-cell counts and disease progression in a Danish cohort of HIV-infected individuals. Copenhagen AIDS cohort.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association - 1 Jun 1998
Eugen-Olsen J, Iversen A K, Benfield T L, Koppelhus U, Garred P
Abstract excerpt
We have investigated the role of the recently described mutation in CCR2b named 64I in relation to HIV resistance, CD4 T-cell counts, and disease progression in Danish individuals by polymerase chain reaction (PCR)-based methods as well as sequenced full-length CXCR4 and CCR5 genes from HIV-infec...
Topics
- Alleles
- CD4 Lymphocyte Count
- CD4-Positive T-Lymphocytes
- Cohort Studies
- DNA Primers
- Denmark
- Disease Progression
- Gene Frequency
- HIV Infections
- HIV-1
- Humans
- Male
- Point Mutation
- Polymerase Chain Reaction