Article
Effects of CCR5-delta32 and CCR2-64I alleles on disease progression of perinatally HIV-1-infected children: an international meta-analysis.
AIDS (London, England) - 25 Jul 2003
Ioannidis John P A, Contopoulos-Ioannidis Despina G, Rosenberg Philip S, Goedert James J, De Rossi Anita, Espanol Teresa, Frenkel Lisa, Mayaux Marie-Jeanne, Newell Marie-Louise, Pahwa Savita G, Rousseau Christine, Scarlatti Gabriella, Sei Shizuko, Sen Luisa, O'Brien Thomas R
Abstract excerpt
OBJECTIVE: Among perinatally infected children, the effects of certain alleles of the CCR5 and CCR2 genes on the rate of disease progression remain unclear. We addressed the effects of CCR5-delta32 and CCR2-64I in an international meta-analysis. METHODS: Genotype data were contributed from 10 studies with 1317 HIV-1-infected children (7263 person-years of follow-up). Time-to-event analyses were performed...
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