Article
Identification of polymorphic loci in the promoter region of the serotonin 5-HT2C receptor gene and their association with obesity and type II diabetes.
Diabetologia - 1 Mar 2000
Yuan X, Yamada K, Ishiyama-Shigemoto S, Koyama W, Nonaka K
Abstract excerpt
AIMS/HYPOTHESIS: Polymorphisms in the upstream region of the 5-HT2C receptor gene could play a part in the development of obesity. METHODS: We screened the upstream region from 27 men by the single strand conformational polymorphism analysis and PCR-direct sequencing and then genotyped 466 non-obese (body mass index < 28 kg/m2) and 123 obese (> or = 28 kg/m2) men including 138 patients with Type II...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
