Article
HOM-C genes, Wnt signaling and axial patterning in the C. elegans posterior ventral epidermis.
Developmental biology - 1 Aug 2009
Li Xin, Kulkarni Rashmi P, Hill Russell J, Chamberlin Helen M
Abstract excerpt
Wnt signaling and HOM-C/Hox genes pattern cell fate along the anterior/posterior axis in many animals. In general, Wnt signaling participates in establishing the anterior/posterior axis, whereas HOM-C genes confer regional identities to cells along the axis. However, recent work in non-bilaterial metazoans suggests that the ancestral patterning system relied on Wnts, with a later co-option of HOM-C genes to...
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