Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of maternal-offspring HLA compatibility, parent-of-origin effects, and noninherited maternal antigen effects for HLA-DRB1 in systemic lupus erythematosus.

Arthritis and rheumatism - 1 Jun 2010

Bronson Paola G, Komorowski Leanne K, Ramsay Patricia P, May Suzanne L, Noble Janelle, Lane Julie A, Thomson Glenys, Claas Frans H, Seldin Michael F, Kelly Jennifer A, Harley John B, Moser Kathy L, Gaffney Patrick M, Behrens Timothy, Criswell Lindsey A, Barcellos Lisa F

Abstract excerpt

OBJECTIVE: Genetic susceptibility to systemic lupus erythematosus (SLE) is well established, with the HLA class II DRB1 and DQB1 loci demonstrating the strongest association. However, HLA may also influence SLE through novel biologic mechanisms in addition to genetic transmission of risk alleles. Evidence for increased maternal-offspring HLA class II compatibility in SLE and differences in maternal versus...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Genetic Predisposition to Disease

Share to HLA-DR Antigens

Share to HLA-DRB1 Chains

Share to Lupus Erythematosus, Systemic

Share to Surveys and Questionnaires

Source

Open in PubMed Open full text

Identifiers

PMID: 20191587
DOI: 10.1002/art.27426
PMCID: PMC2948464

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of maternal-offspring HLA compatibility, parent-of-origin effects, and noninherited maternal antigen effects for HLA-DRB1 in systemic lupus erythematosus.PMID 20191587Read ↗

Analysis of maternal-offspring HLA compatibility, parent-of-origin and non-inherited maternal effects for the classical HLA loci in type 1 diabetes.Semantic proximity Read ↗

Maternal HLA class II compatibility in men with systemic lupus erythematosus.Semantic proximity Read ↗

Maternal - offspring HLA-DRB1 compatibility in multiple sclerosis.Semantic proximity Read ↗

A Child's HLA-DRB1 genotype increases maternal risk of systemic lupus erythematosus.Semantic proximity Read ↗

Parent-of-origin effects at the major histocompatibility complex in multiple sclerosis.Semantic proximity Read ↗

Parental history of lupus and rheumatoid arthritis and risk in offspring in a nationwide cohort study: does sex matter?Semantic proximity Read ↗

The analysis of parental origin of alleles may detect susceptibility loci for complex disorders.Semantic proximity Read ↗

Non-random mating, parent-of-origin, and maternal-fetal incompatibility effects in schizophrenia.Semantic proximity Read ↗

Noninherited maternal antigens do not play a role in rheumatoid arthritis susceptibility in Europe. European Consortium on Rheumatoid Arthritis Families.Semantic proximity Read ↗

Parent-of-origin effects in MSSemantic proximity Read ↗

Maternal-Foetal HLA-DQB1 Incompatibility Is Associated With Pregnancy-Induced Hypertensive Disorders in a Genetically Isolated Population.Semantic proximity Read ↗

Preferential transmission of genetic risk variants of candidate loci at 6p21 from asymptomatic grandparents to mothers of children with neonatal lupus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.