Article
A single naturally processed measles virus peptide fully dominates the HLA-A*0201-associated peptide display and is mutated at its anchor position in persistent viral strains.
European journal of immunology - 1 Apr 2000
van Els C A, Herberts C A, van der Heeft E, Poelen M C, van Gaans-van den Brink J A, van der Kooi A, Hoogerhout P, Jan ten Hove G, Meiring H D, de Jong A P
Abstract excerpt
We studied the natural MHC class I display of measles virus (MV) epitopes. Peptide ligands associated with HLA-A*0201 were purified from a B lymphoblastoid cell line prior to and after infection with MV. Infection-induced peptides were revealed using microcapillary reversed phase high performance liquid chromatography electrospray ionization/mass spectrometry (microLC-ESI/MS) by subtraction of the "infected" and...
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