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Article

Effects of gender and genotype on the phenotypic expression of nonmodulating essential hypertension.

Kidney international - 1 Apr 2000

Williams G H, Fisher N D, Hunt S C, Jeunemaitre X, Hopkins P N, Hollenberg N K

Abstract excerpt

Nonmodulation describes a subset of the normal/high renin essential hypertensive population. It is an inherited trait. This report reviews the genetic and gender data recently available that discuss the modification of the expression of the nonmodulating phenotype. Both the adrenal and the renal blood flow markers for nonmodulation are associated with a single nucleotide polymorphism (SNP) in the coding region of...

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PMID: 10760074
DOI: 10.1046/j.1523-1755.2000.00982.x

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Source receipt: pubmed, retrieved 7 Sept 2026.

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