Article
Genetic determinants of nonmodulating hypertension.
Hypertension (Dallas, Tex. : 1979) - 1 Nov 2003
Kosachunhanun Natapong, Hunt Steven C, Hopkins Paul N, Williams Roger R, Jeunemaitre Xavier, Corvol Pierre, Ferri Claudio, Mortensen Richard M, Hollenberg Norman K, Williams Gordon H
Abstract excerpt
We sought to determine whether genes of the renin-angiotensin-aldosterone system can predict the nonmodulating intermediate phenotype in essential hypertension. Aldosterone responses to angiotensin II were assessed in 298 subjects with hypertension. Subjects were genotyped at the angiotensinogen M235T, angiotensin-converting enzyme I/D, aldosterone synthase C-344 T, renin, angiotensin II type 1 receptor, and...
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