Article
Aldosterone stimulation by angiotensin II : influence of gender, plasma renin, and familial resemblance.
Hypertension (Dallas, Tex. : 1979) - 1 Mar 2000
Giacché M, Vuagnat A, Hunt S C, Hopkins P N, Fisher N D, Azizi M, Corvol P, Williams G H, Jeunemaitre X
Abstract excerpt
The aldosterone response to infused angiotensin II (Ang II) in patients receiving a low-salt diet has been described as an important phenotype for genetic studies on human hypertension. The objectives of the present study were to determine the parameters that influence this intermediate phenotype as a quantitative trait and to assess the importance of its familial resemblance in hypertensive sibling pairs. Two...
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